Recombinant Mouse Transmembrane protease serine 11A (Tmprss11a), partial
Product Specifications
Product Name Alternative
(Airway trypsin-like protease 1) (Serine protease DESC3) (DESC-3)
Abbreviation
Recombinant Mouse Tmprss11a protein, partial
Gene Name
Tmprss11a
UniProt
Q3UQ41
Expression Region
45-389aa
Organism
Mus musculus (Mouse)
Target Sequence
QVNSNSGQKSSNQLKDLQETNENLVDEIFIDSALNNRYIKNHVVGLTPEEDDTKADIVMVFQPPATGRRTVGKKTHHSILDQKTRNARALPADVSLVQVKDCGKRAIPLIANRIVSGNPAAKGAWPWQVSLQRSNIHQCGGTLIGNMWVVTAAHCFRTNSNPRQWTLSFGTTINPPLMKRDVRRIIMHERYRPPARDHDIALVQFSPRVTFSDEVRRICLPEPSASFPPNSTVYITGFGALYYGGESQNELREARVQIISNDICKKRHVYGNEIKRGMFCAGFLEGNYDACRGDSGGPLVIRDNKDTWYLIGIVSWGDNCGQKNKPGVYTQVTYYRHWIASKTGL
Tag
N-terminal 10xHis-tagged and C-terminal Myc-tagged
Type
Developed Protein
Source
E.coli
Field of Research
Cell Biology
Relevance
Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest.
Endotoxin
Not test
Purity
Greater than 85% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight
46.2 kDa
References & Citations
"Mouse DESC1 is located within a cluster of seven DESC1-like genes and encodes a type II transmembrane serine protease that forms serpin inhibitory complexes." Hobson J.P., Netzel-Arnett S., Szabo R., Rehault S.M., Church F.C., Strickland D.K., Lawrence D.A., Antalis T.M., Bugge T.H. J. Biol. Chem. 279:46981-46994 (2004)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Product MSDS
https://www.cusabio.com/msds/12932872/
Protein Length
Partial
Available Sizes
Curated Selection
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