BTK inhibitor 17
BTK inhibitor 17 is a potent and orally active irreversible BTK inhibitor with an IC50 of 2.1 nM. BTK inhibitor 17 can be used for rheumatoid arthritis research[1].
Product Specifications
CAS Number
[1858206-76-4]
UNSPSC
12352005
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/btk-inhibitor-17.html
Purity
99.53
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(N([C@H]2CN(C(C=C)=O)CCC2)N=C3C4=CC=C(OC5=CC=CC=C5)C=C4)=C3C(N)=NN1
Molecular Formula
C25H24N6O3
Molecular Weight
456.50
References & Citations
[1]Xuejun Zhang, et al. Discovery and Evaluation of Pyrazolo[3,4- d]pyridazinone as a Potent and Orally Active Irreversible BTK Inhibitor. ACS Med Chem Lett. 2019 Dec 11;11 (10) :1863-1868.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K6094703 1.0 µg DNA
Snip1 sgRNA CRISPR Lentivector (Rat) (Target 2)
Sign In for Pricing
View Details 
251759-HRP 100 µL
SLC45A2 (Solute Carrier Family 45, Member 2, 1A1, AIM1, MATP, SHEP5) (HRP)
Sign In for Pricing
View Details ![Rabbit Polyclonal FDX1L Antibody [DyLight 550]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
MBS1353704-01 0.02 mg (E-Coli)
Recombinant Neorickettsia sennetsu Probable rRNA maturation factor (NSE_0249)
Sign In for Pricing
View Details MBS1353704-02 0.1 mg (E-Coli)
Recombinant Neorickettsia sennetsu Probable rRNA maturation factor (NSE_0249)
Sign In for Pricing
View Details MBS1353704-03 0.02 mg (Yeast)
Recombinant Neorickettsia sennetsu Probable rRNA maturation factor (NSE_0249)
Sign In for Pricing
View Details