Levamisole (hydrochloride)
Levamisole ((-) -Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV.
Product Specifications
CAS Number
16595-80-5
Product Name Alternative
(-) -Tetramisole hydrochloride
UNSPSC
12352005
Hazard Statement
H301
Target
HSV; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
Neuroscience-Neuromodulation
Field of Research
Infection; Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Levamisole-hydrochloride.html
Purity
99.96
Solubility
DMSO : 15.5 mg/mL (ultrasonic; warming) |Ethanol : 12.5 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
[H]Cl.C12=N[C@@H](C3=CC=CC=C3)CN1CCS2
Molecular Formula
C11H13ClN2S
Molecular Weight
240.76
Precautions
H301
References & Citations
[1]Centers for Disease Control and Prevention (CDC) . Agranulocytosis associated with cocaine use - four States, March 2008-November 2009.MMWR Morb Mortal Wkly Rep. 2009 Dec 18;58 (49) :1381-5.|[2]Zhu NY, et al. Agranulocytosis after consumption of cocaine adulterated with levamisole. Ann Intern Med. 2009 Feb 17;150 (4) :287-9.|[3]Van Belle H.
 Alkaline phosphatase. I. Kinetics and inhibition by levamisole of purified isoenzymes from humans. Clin Chem. 1976 Jul;22 (7) :972-6.|[4]Friedlaender MH, et al. The treatment of herpetic reinfection with levamisole. Am J Ophthalmol. 1978 Aug;86 (2) :245-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HSV-1
Citation 01
BioRxiv. 2023 Oct 15.|bioRxiv. 2025 Jul 24.|bioRxiv. 2025 Nov 1.|Environ Sci Pollut Res Int. 2023 Jan;30 (5) :12522-12531.|Int J Biol Macromol. 2025 Apr 17;310 (Pt 1) :143312.|J Ethnopharmacol. 2024 Jun 3:118406.|ACS Environ Au. 2025 Aug 8.|Anal Chem. 2025 Jun 3;97 (21) :11099-11109.|EBioMedicine. 2025 Sep:119:105914.|Phytomed Plus. 2025 Aug 23.|Rapid Commun Mass Spectrom. 2023 Feb 15;37 (3) :e9430.
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