Levamisole (hydrochloride)

Levamisole ((-) -Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV.

Product Specifications

CAS Number

[16595-80-5]

Product Name Alternative

(-) -Tetramisole hydrochloride

UNSPSC

12352005

Hazard Statement

H301

Target

HSV; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

Neuroscience-Neuromodulation

Field of Research

Infection; Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Levamisole-hydrochloride.html

Purity

99.96

Solubility

DMSO : 15.5 mg/mL (ultrasonic; warming) |Ethanol : 12.5 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

[H]Cl.C12=N[C@@H](C3=CC=CC=C3)CN1CCS2

Molecular Formula

C11H13ClN2S

Molecular Weight

240.76

Precautions

H301

References & Citations

[1]Centers for Disease Control and Prevention (CDC) . Agranulocytosis associated with cocaine use - four States, March 2008-November 2009.MMWR Morb Mortal Wkly Rep. 2009 Dec 18;58 (49) :1381-5.|[2]Zhu NY, et al. Agranulocytosis after consumption of cocaine adulterated with levamisole. Ann Intern Med. 2009 Feb 17;150 (4) :287-9.|[3]Van Belle H. Alkaline phosphatase. I. Kinetics and inhibition by levamisole of purified isoenzymes from humans. Clin Chem. 1976 Jul;22 (7) :972-6.|[4]Friedlaender MH, et al. The treatment of herpetic reinfection with levamisole. Am J Ophthalmol. 1978 Aug;86 (2) :245-9.