Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Cardamonin

Cardamonin can be found from cardamom, and can target various signaling molecules, transcriptional factors, cytokines and enzymes. Cardamonin can inhibit mTOR, NF-κB, Akt, STAT3, Wnt/β-catenin and COX-2. Cardamonin shows anticancer, anti-inflammatory, antimicrobial and antidiabetic activities[1][2].

Product Specifications

CAS Number

18956-16-6

Product Name Alternative

Cardamomin; Alpinetin chalcone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Bcl-2 Family; NF-κB; STAT; Wnt; β-catenin

Type

Natural Products

Related Pathways

Apoptosis; JAK/STAT Signaling; NF-κB; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/cardamonin-1.html

Purity

98.38

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=C(OC)C=C(O)C=C1O)/C=C/C2=CC=CC=C2

Molecular Formula

C16H14O4

Molecular Weight

270.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Javaria Nawaz, et al. Cardamonin: A new player to fight cancer via multiple cancer signaling pathways. Life Sci. 2020 Jun 1;250:117591.|[2]Kai Wang, et al. Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway. Biochem Pharmacol. 2018 Sep;155:494-509.|[3]Zheng Wang, et al. Cardamonin exerts anti-gastric cancer activity via inhibiting LncRNA-PVT1-STAT3 axis. Biosci Rep. 2019 May 17;39 (5) :BSR20190357.|[4]Wang Qi, et al. Cardamonin protects against doxorubicin-induced cardiotoxicity in mice by restraining oxidative stress and inflammation associated with Nrf2 signaling. Biomed Pharmacother. 2020 Feb;122:109547.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

HACE1 Antibody
orb2672448-01 50 µL

HACE1 Antibody

Sign In for Pricing
View Details
HACE1 Antibody
orb2672448-02 100 µL

HACE1 Antibody

Sign In for Pricing
View Details
HACE1 Antibody
orb2672448-03 200 µL

HACE1 Antibody

Sign In for Pricing
View Details
HLA-DMB polyclonal antibody
BS79061-01 50 µL

HLA-DMB polyclonal antibody

Sign In for Pricing
View Details
HLA-DMB polyclonal antibody
BS79061-02 100 µL

HLA-DMB polyclonal antibody

Sign In for Pricing
View Details
Pycr1 sgRNA CRISPR Lentivector set (Rat)
K6306701 3x 1.0 µg

Pycr1 sgRNA CRISPR Lentivector set (Rat)

Sign In for Pricing
View Details