Grp94 Inhibitor-2
Grp94 Inhibitor-2 (compound 23), a cyclopropane analog, exhibits high affinity for glucose-regulated protein 94 (Grp94) with a Kd of 0.48 µM and 0.65 µM for Grp94 and Hsp90α, respectively[1].
Product Specifications
UNSPSC
12352211
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/grp94-inhibitor-2.html
Smiles
FC(C=C1)=CC=C1CC2=C(CCC3=C(C(N[C@@H]4C[C@@H](O)C4)=O)C(O)=CC(O)=C3Cl)C=CC=C2
Molecular Formula
C26H25ClFNO4
Molecular Weight
469.93
References & Citations
[1]cyclopropane analog, exhibits high affinity for glucose-regulated protein 94 (Grp94) with a Kd of 0.48 µM and 0.65 µM for Grp94 and Hsp90α
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSP90
Curated Selection
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