Pyruvate Carboxylase-IN-4
Pyruvate Carboxylase-IN-4 (Compd 8V) is a potent and competitive Pyruvate Carboxylase inhibitor with an IC50 of 4.3 μM[1].
Product Specifications
CAS Number
[2369048-06-4]
UNSPSC
12352005
Target
Pyruvate Carboxylase (PC)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pyruvate-carboxylase-in-4.html
Smiles
O/C(C(O)=O)=C\C1=NC2=C(C=CC=C2)C=C1
Molecular Formula
C12H9NO3
Molecular Weight
215.20
References & Citations
[1]Burkett DJ, et al. Evaluation of α-hydroxycinnamic acids as pyruvate carboxylase inhibitors. Bioorg Med Chem. 2019 Sep 15;27 (18) :4041-4047.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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