Pyruvate Carboxylase-IN-4

Pyruvate Carboxylase-IN-4 (Compd 8V) is a potent and competitive Pyruvate Carboxylase inhibitor with an IC50 of 4.3 μM[1].

Product Specifications

CAS Number

[2369048-06-4]

UNSPSC

12352005

Target

Pyruvate Carboxylase (PC)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pyruvate-carboxylase-in-4.html

Smiles

O/C(C(O)=O)=C\C1=NC2=C(C=CC=C2)C=C1

Molecular Formula

C12H9NO3

Molecular Weight

215.20

References & Citations

[1]Burkett DJ, et al. Evaluation of α-hydroxycinnamic acids as pyruvate carboxylase inhibitors. Bioorg Med Chem. 2019 Sep 15;27 (18) :4041-4047.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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