Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ticagrelor

Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation.

Product Specifications

CAS Number

274693-27-5

Product Name Alternative

AZD6140; AR-C 126532XX

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

P2Y Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Ticagrelor.html

Purity

99.98

Solubility

DMSO : ≥ 50 mg/mL

Smiles

O[C@H]1[C@@H](O)[C@H](N2N=NC3=C(N[C@H]4[C@H](C5=CC=C(F)C(F)=C5)C4)N=C(SCCC)N=C32)C[C@@H]1OCCO

Molecular Formula

C23H28F2N6O4S

Molecular Weight

522.57

Precautions

H302, H315, H319, H335

References & Citations

[1]Aungraheeta R, et al. Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor. Blood. 2016 Dec 8;128 (23) :2717-2728.|[2]Gebremeskel S, et al. The reversible P2Y12 inhibitor ticagrelor inhibits metastasis and improves survival in mouse models of cancer. Int J Cancer. 2015 Jan 1;136 (1) :234-40.|[3]Sugidachi A, et al. A comparison of the pharmacological profiles of prasugrel and ticagrelor assessed by platelet aggregation, thrombus formation and haemostasis in rats. Br J Pharmacol. 2013 May;169 (1) :82-9.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

P2Y12 Receptor

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Etv3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
K7476806 1.0 µg DNA

Etv3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

Sign In for Pricing
View Details
Nucleon PhytoPure Genomic DNA Extraction Kit 50 preps x 1g
RPN8511 1 Each

Nucleon PhytoPure Genomic DNA Extraction Kit 50 preps x 1g

Sign In for Pricing
View Details
Wnt5a Mouse siRNA Oligo Duplex (Locus ID 22418)
SR412815 1 Kit

Wnt5a Mouse siRNA Oligo Duplex (Locus ID 22418)

Sign In for Pricing
View Details
ISCA1 Human shRNA Lentiviral Particle (Locus ID 81689)
TL319531V 500 µL Each

ISCA1 Human shRNA Lentiviral Particle (Locus ID 81689)

Sign In for Pricing
View Details
Sqrdl 3'UTR Luciferase Stable Cell Line
TU221152 1.0 mL

Sqrdl 3'UTR Luciferase Stable Cell Line

Sign In for Pricing
View Details
Mouse Monoclonal APE Antibody (13B8E5C2) [mFluor Violet 450 SE]
NB100-116MFV450 0.1 mL

Mouse Monoclonal APE Antibody (13B8E5C2) [mFluor Violet 450 SE]

Sign In for Pricing
View Details