LQZ-7I
LQZ-7I is a survivin-targeting inhibitor. LQZ-7I inhibits survivin dimerization. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors[1].
Product Specifications
CAS Number
[195822-23-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H320, H335
Target
Survivin
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lqz-7i.html
Concentration
10mM
Purity
99.78
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
FC1=CC=C(NC2=NC3=CC=CC=C3N=C2NC4=CC=C(F)C=C4)C=C1
Molecular Formula
C20H14F2N4
Molecular Weight
348.35
Precautions
H302, H315, H320, H335
References & Citations
[1]Robert Peery, et al. Synthesis and Identification of a Novel Lead Targeting Survivin Dimerization for Proteasome-Dependent Degradation. J Med Chem. 2020 Jun 9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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