Perlapine

Perlapine is a potent muscarinic DREADD (Designer Receptors Exclusively Activated by Designer agents) agonist Perlapine exhibits >10000-fold selectivity for hM3Dq over hM3 receptors[1].

Product Specifications

CAS Number

[1977-11-3]

Product Name Alternative

MP-11

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H413

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/perlapine.html

Purity

99.6

Solubility

10 mM in DMSO

Smiles

CN1CCN(C2=NC(C=CC=C3)=C3CC4=CC=CC=C24)CC1

Molecular Formula

C19H21N3

Molecular Weight

291.39

Precautions

H302, H315, H319, H413

References & Citations

[1]Chen X, et al. The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs. ACS Chem Neurosci. 2015 Mar 18;6 (3) :476-84.