SM-130686

SM-130686 is an oxindole derivative and an active GH secretagogue (GHS) . SM-130686 stimulates GH release with a Half-maximum stimulation of 6.3 nM. SM-130686 has an orally active[1].

Product Specifications

CAS Number

[259667-25-9]

UNSPSC

12352005

Target

GHSR

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sm-130686.html

Smiles

O[C@]1(C2=C(C=CC=C2)Cl)C3=C(C(F)(F)F)C=C(C(N)=O)C=C3N(C1=O)CCN(CC)CC.Cl

Molecular Formula

C22H24Cl2F3N3O3

Molecular Weight

506.35

References & Citations

[1]J Nagamine, et al. Pharmacological profile of a new orally active growth hormone secretagogue, SM-130686. J Endocrinol. 2001 Dec;171 (3) :481-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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