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IL-33, Canine

Product Specifications

UNSPSC Description

IL-33 Protein activates NF-kappa-B and MAPK signaling, inducing Th2 cell maturation and cytokine secretion. It activates mast cells, basophils, eosinophils, and natural killer cells, acting as a chemoattractant for Th2 cells. IL-33 preserves Krebs cycle integrity, reducing reactive oxygen species production. In quiescent endothelial cells, IL-33 acts as a transcriptional repressor, but is lost upon angiogenic or pro-inflammatory activation. IL-33 Protein, Canine is the recombinant canine-derived IL-33 protein, expressed by E. coli , with N-Met labeled tag. The total length of IL-33 Protein, Canine is 154 a.a., with molecular weight of ~19 kDa.

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-33-protein-canine.html

Purity

95.50

Smiles

SIQEYSASLS TYNDQSITFV FEDGSYEIYV EDLRKGQEKD KVLFRYYDSQ SPSHETGDDV DGQTLLVNLS PTKDKDFLLH ANNEEHSVEL QKCENQLPDQ AFFLLHRKSS ECVSFECKNN PGVFIGVKDN HLALIKVGDQ TKDSYIEKTI FKLS

Molecular Weight

Approximately 19 kDa

Shipping Conditions

Blue Ice

Storage Conditions

Stored at -20°C for 2 years

Available Sizes

Curated Selection

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