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Anthopleurin-A (TFA)

Anthopleurin-A TFA is a soidum channel toxin. Anthopleurin-A TFA is selective for cardiac channels and has cardiotonic effect. Anthopleurin-A TFA can be isolated from the sea anemone[1][2].

Product Specifications

UNSPSC

12352209

Target

Sodium Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/anthopleurin-a-tfa.html

Purity

98.39

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(CN)N[C@H](C(N[C@H](C(NC(C(NC(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(NCC(N[C@H](C(N3C(C(NC(C(NCC(NC(C(NC(C(NC4CC(N)=O)=O)CC5=CNC=N5)=O)CC6=CNC7=CC=CC=C67)=O)=O)CO)=O)CCC3)=O)CSSC[C@H](NC8=O)C(N[C@H](C(N[C@H](C(O)=O)CCC(N)=O)=O)CCCCN)=O)=O)=O)CO)=O)CCC2)=O)CC9=CC=C(O)C=C9)=O)CC(C)C)=O)CC%10=CNC%11=CC=CC=C%10%11)=O)CC(C)C)=O)[C@@H](C)O)=O)=O)CO)=O)CC(C)C)=O)[C@@H](C)O)=O)CC(N)=O)=O)=O)CCCNC(N)=N)=O)C(C)C)=O)CO)=O)CCC1)=O)=O)CC(O)=O)=O)CO)=O)CC(O)=O)=O)CSSC[C@H](NC4=O)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N%12[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]%13CC%14=CNC%15=CC=CC=C%14%15)=O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)CCC%12)=O)=O)CC%16=CNC=N%16)=O)C)=O)CCCCN)=O)=O)CC(C)C)=O)CSSC[C@@H]8NC%13=O)=O)CO)=O)C(C)C.OC(C(F)(F)F)=O.[x]

Molecular Formula

C220H326N64O67S6.xC2HF3O2

Molecular Weight

5131.72 (free base)

References & Citations

[1]Honma T, Shiomi K. Peptide toxins in sea anemones: structural and functional aspects. Mar Biotechnol (NY) . 2006 Jan-Feb;8 (1) :1-10.|[2]Scriabine A, et al. Cardiotonic effects of anthopleurin-A, a polypeptide from a sea anemone. J Cardiovasc Pharmacol. 1979 Sep-Oct;1 (5) :571-83.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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