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KRAS inhibitor-35

KRAS inhibitor-35 (compound 72) is a KRAS inhibitor, with IC50 of 2 nM. KRAS inhibitor-35 can be used in tumor research[1].

Product Specifications

CAS Number

3030078-96-4

UNSPSC

12352101

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kras-inhibitor-35.html

Smiles

C#CC1=C(C=CC2=C1C(C3=C(C4=C(C(N5CCN(CC5)C(/C(F)=C/C6=NC=CS6)=O)=NC(OC[C@]78C[C@@H](F)CN7CCC8)=N4)C=C3)F)=CC(O)=C2)F

Molecular Formula

C38H32F4N6O3S

Molecular Weight

728.76

References & Citations

[1]Matthew Leo CONDAKES, et al. Kras inhibitors. WO2024036270A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

K-Ras

Frequently Asked Questions

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