KRAS inhibitor-35
KRAS inhibitor-35 (compound 72) is a KRAS inhibitor, with IC50 of 2 nM. KRAS inhibitor-35 can be used in tumor research[1].
Product Specifications
CAS Number
3030078-96-4
UNSPSC
12352101
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-inhibitor-35.html
Smiles
C#CC1=C(C=CC2=C1C(C3=C(C4=C(C(N5CCN(CC5)C(/C(F)=C/C6=NC=CS6)=O)=NC(OC[C@]78C[C@@H](F)CN7CCC8)=N4)C=C3)F)=CC(O)=C2)F
Molecular Formula
C38H32F4N6O3S
Molecular Weight
728.76
References & Citations
[1]Matthew Leo CONDAKES, et al. Kras inhibitors. WO2024036270A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
Frequently Asked Questions
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