Amino-PEG6-alcohol
Amino-PEG6-alcohol is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG6-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[39160-70-8]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amino-peg6-alcohol.html
Purity
99.85
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OCCOCCOCCOCCOCCOCCN
Molecular Formula
C12H27NO6
Molecular Weight
281.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker; PEG Linkers
Available Sizes
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