(S)-BRD9500
Product Specifications
UNSPSC Description
(S)-BRD9500 is the isomer of BRD9500 (HY-136350), and can be used as an experimental control. BRD9500 is an orally active phosphodiesterases 3 (PDE3) inhibitor with IC50s of 10 and 27 nM for PDE3A and PDE3B, respectively. Antitumor activity[1].
Target Antigen
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-brd9500.html
Smiles
O=C1C[C@H](C)C(C2=CC=C(N3CCOCC3)C(F)=C2)=NN1
Molecular Weight
291.326
References & Citations
[1]Timothy A Lewis, et al. Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing. ACS Med Chem Lett. 2019 Oct 18;10(11):1537-1542.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-136350B/S-BRD9500-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-136350B/S-BRD9500-SDS-MedChemExpress.pdf
CAS Number
1630760-76-7
Available Sizes
Curated Selection
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