17-ODYA
17-ODYA is a CYP450 ω-hydroxylase inhibitor. 17-ODYA is also a potent inhibitor (IC50[1][2][3]. 17-ODYA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
34450-18-5
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Cytochrome P450
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/17-odya.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C#CCCCCCCCCCCCCCCCC(O)=O
Molecular Formula
C18H32O2
Molecular Weight
280.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Jiang S, et al. β-adrenergic Receptor-stimulated Cardiac Myocyte Apoptosis: Role of Cytochrome P450 ω-hydroxylase. J Cardiovasc Pharmacol. 2017;70 (2) :94-101. |[2]Zou AP, et al. Effects of 17-octadecynoic acid, a suicide-substrate inhibitor of cytochrome P450 fatty acid omega-hydroxylase, on renal function in rats. J Pharmacol Exp Ther. 1994;268 (1) :474-481.|[3]Nithipatikom K, et al. Inhibition of cytochrome P450omega-hydroxylase: a novel endogenous cardioprotective pathway. Circ Res. 2004;95 (8) :e65-e71.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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