17-ODYA
Product Specifications
UNSPSC Description
17-ODYA is a CYP450 ω-hydroxylase inhibitor. 17-ODYA is also a potent inhibitor (IC50[1][2][3]. 17-ODYA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
Apoptosis; Cytochrome P450
Type
Reference compound
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/17-odya.html
Purity
98.0
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
C#CCCCCCCCCCCCCCCCC(O)=O
Molecular Weight
280.45
References & Citations
[1]Jiang S, et al. β-adrenergic Receptor-stimulated Cardiac Myocyte Apoptosis: Role of Cytochrome P450 ω-hydroxylase. J Cardiovasc Pharmacol. 2017;70(2):94-101. |[2]Zou AP, et al. Effects of 17-octadecynoic acid, a suicide-substrate inhibitor of cytochrome P450 fatty acid omega-hydroxylase, on renal function in rats. J Pharmacol Exp Ther. 1994;268(1):474-481.|[3]Nithipatikom K, et al. Inhibition of cytochrome P450omega-hydroxylase: a novel endogenous cardioprotective pathway. Circ Res. 2004;95(8):e65-e71.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101016/17-ODYA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101016/17-ODYA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
34450-18-5
Available Sizes
Curated Selection
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