Lubabegron

Lubabegron is a potent modulator of β-adrenergic receptor (β-AR) . Lubabegron demonstrates antagonistic behavior at the β1 and β 2 receptor subtypes and agonistic behavior at the β 3 receptor subtype in cattle. Lubabegron reduces NH3 gas emissions from an animal or its waste. Lubabegron is available as an animal supplement[1][2].

Product Specifications

CAS Number

[391920-32-4]

Product Name Alternative

LY-488756

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/lubabegron.html

Purity

98.40

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N#CC1=CC=CN=C1OC2=CC=C(C=C2)CC(NC[C@@H](COC3=CC=CC=C3C4=CC=CS4)O)(C)C

Molecular Formula

C29H29N3O3S

Molecular Weight

499.62

References & Citations

[1]Kube JC, et al. Effects of various doses of lubabegron on calculated ammonia gas emissions, growth performance, and carcass characteristics of beef cattle during the last 56 days of the feeding period [published correction appears in Transl Anim Sci. 2021 Nov 15;5 (4) :txab210]. Transl Anim Sci. 2021;5 (3) :txab137. |[2]Corona A K, et al. The Impact of Lubabegron Supplementation on Meat Quality of Feedlot Steers. Meat and Muscle Biology, 2025, 9 (1) .