AK-4
AK-4 is a glucose-lowering agent, acting function as a mitochondrial uncoupler[1].
Product Specifications
UNSPSC
12352005
Target
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ak-4.html
Smiles
ClC(C=C(Cl)C=C1)=C1CN2C3=CC=CC=C3C(/C=C4SC(N(CC(O)=O)C\4=O)=O)=C2
Molecular Formula
C21H14Cl2N2O4S
Molecular Weight
461.32
References & Citations
[1]Kousaxidis A, et al. Rational design and synthesis of novel N-benzylindole-based epalrestat analogs as selective aldose reductase inhibitors: An unexpected discovery of a new glucose-lowering agent (AK-4) acting as a mitochondrial uncoupler. Eur J Med Chem. 2025 Jan 5;281:117035.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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