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(E/Z) -SIB-1893

(E/Z) -SIB-1893 is a racemic compound of (E) -SIB-1893 and (Z) -SIB-1893 isomers. (E) -SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist[1].

Product Specifications

CAS Number

6266-99-5

UNSPSC

12352005

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/e-z-sib-1893.html

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=NC(/C=C/C2=CC=CC=C2)=CC=C1

Molecular Formula

C14H13N

Molecular Weight

195.26

References & Citations

[1]Łuszczki JJ, et al. Non-competitive metabotropic glutamate subtype 5 receptor antagonist (SIB-1893) decreases body temperature in rats. Pharmacol Rep. 2005;57 (6) :795-801.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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