(E/Z) -SIB-1893
(E/Z) -SIB-1893 is a racemic compound of (E) -SIB-1893 and (Z) -SIB-1893 isomers. (E) -SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist[1].
Product Specifications
CAS Number
6266-99-5
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/e-z-sib-1893.html
Purity
99.80
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=NC(/C=C/C2=CC=CC=C2)=CC=C1
Molecular Formula
C14H13N
Molecular Weight
195.26
References & Citations
[1]Łuszczki JJ, et al. Non-competitive metabotropic glutamate subtype 5 receptor antagonist (SIB-1893) decreases body temperature in rats. Pharmacol Rep. 2005;57 (6) :795-801.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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