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Panamesine

Panamesine (EMD 57445) is a sigma receptor ligand, which has a high affinity (IC50 6 nM) and selectivity for sigma binding sites. Panamesine is a potential atypical neuroleptic agent[1].

Product Specifications

CAS Number

139225-22-2

Product Name Alternative

EMD 57445

UNSPSC

12352005

Target

Sigma Receptor

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/panamesine.html

Concentration

10mM

Purity

99.43

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1O[C@@H](CN2CCC(O)(C3=CC=C(OCO4)C4=C3)CC2)CN1C5=CC=C(OC)C=C5

Molecular Formula

C23H26N2O6

Molecular Weight

426.46

References & Citations

[1]N Dahmen, et al. Induction of C-Fos Gene Expression by the Selective Sigma Receptor Ligand EMD 57445 in Rat Brain. Eur Neuropsychopharmacol. 1996 Aug;6 (3) :237-43.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

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