α-Muricholic acid-d5

α-Muricholic acid-d5 is the deuterium labeled α-Muricholic acid. α-Muricholic acid is the most abundant primary bile acid in rodents[1][2].

Product Specifications

CAS Number

[2725726-61-2]

Product Name Alternative

MK-0364

UNSPSC

12352211

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease; Endocrinology

Solubility

10 mM in DMSO

Smiles

C[C@@]([C@]1([H])[C@H](O)[C@H]2O)(CC([2H])([2H])[C@](O)([2H])C1([2H])[2H])[C@]3([H])[C@]2([H])[C@@](CC[C@]4([H])[C@H](C)CCC(O)=O)([H])[C@]4(C)CC3

Molecular Formula

C24H35D5O5

Molecular Weight

413.60

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Eyssen HJ, et al. Sulfate bile acids in germ-free and conventional mice. Eur J Biochem. 1976 Jul 15;66 (3) :507-14.|[3]Watanabe K, et al. Dietary soybean protein ameliorates high-fat diet-induced obesity by modifying the gut microbiota-dependent biotransformation of bile acids. PLoS One. 2018 Aug 13;13 (8) :e0202083.