α-Muricholic acid-d5
α-Muricholic acid-d5 is the deuterium labeled α-Muricholic acid. α-Muricholic acid is the most abundant primary bile acid in rodents[1][2].
Product Specifications
CAS Number
[2725726-61-2]
Product Name Alternative
MK-0364
UNSPSC
12352211
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease; Endocrinology
Solubility
10 mM in DMSO
Smiles
C[C@@]([C@]1([H])[C@H](O)[C@H]2O)(CC([2H])([2H])[C@](O)([2H])C1([2H])[2H])[C@]3([H])[C@]2([H])[C@@](CC[C@]4([H])[C@H](C)CCC(O)=O)([H])[C@]4(C)CC3
Molecular Formula
C24H35D5O5
Molecular Weight
413.60
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Eyssen HJ, et al. Sulfate bile acids in germ-free and conventional mice. Eur J Biochem. 1976 Jul 15;66 (3) :507-14.|[3]Watanabe K, et al. Dietary soybean protein ameliorates high-fat diet-induced obesity by modifying the gut microbiota-dependent biotransformation of bile acids. PLoS One. 2018 Aug 13;13 (8) :e0202083.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115433S/
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Curated Selection
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