Ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid
Selected Variant
HY-N3810-01
Size: 1 mg
Ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF) . The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds[1].
Product Specifications
CAS Number
57719-81-0
UNSPSC
12352211
Target
Tyrosinase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ent-11α-hydroxy-15-oxokaur-16-en-19-oic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C1C([C@@]2([H])C[C@]13[C@]([C@@H](O)C2)([H])[C@]4([C@]([C@@](C)(CCC4)C(O)=O)([H])CC3)C)=C
Molecular Formula
C20H28O4
Molecular Weight
332.43
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Price
Frequently Asked Questions
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