MANS peptide
MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis[1].
Product Specifications
CAS Number
479482-23-0
UNSPSC
12352209
Target
MARCKS; PKC
Type
Peptides
Related Pathways
Cytoskeleton; Epigenetics; TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mans-peptide.html
Purity
99.85
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC(CNC(CCCCCCCCCCCCC)=O)=O)C)=O)CCC(N)=O)=O)=O)CO)=O)CCCCN)=O)[C@@H](C)O)=O)C)=O)C)=O)CCCCN)=O)=O)CCC(O)=O)=O)C)=O)C)=O)C)=O)CCC(O)=O)=O)CCCNC(=N)N)(=O)N2[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)C(C)C)=O)C)=O)C)=O)CCC(O)=O)=O)=O)CCC2
Molecular Formula
C111H184N30O35
Molecular Weight
2498.83
References & Citations
[1]Chen CH, et al., A peptide that inhibits function of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis. Oncogene. 2014 Jul 10;33 (28) :3696-706.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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