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Angiotensin II type 1 receptor (181-187)

Angiotensin II type 1 receptor (181-187) is a 9-amino acid sequence of the second extracellular loop of angiotensin II (Ang II) in the renin-angiotensin system. Angiotensin II type 1 receptor (181-187) serves as the localization epitope of angiotensin II receptor autoantibodies (AT1RaAb) and is used to detect and quantify AT1RaAb levels in serum[1].

Product Specifications

CAS Number

275359-37-0

UNSPSC

12352209

Target

Angiotensin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/angiotensin-ii-type-1-receptor-181-187.html

Smiles

OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N[C@H](C(O)=O)CCC(N)=O)=O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](N)C)=O)CC2=CC=CC=C2)=O)CC3=CN=CN3)=O

Molecular Formula

C40H52N10O13

Molecular Weight

880.90

References & Citations

[1]Abadir, et al. "Discovery and validation of agonistic angiotensin receptor autoantibodies as biomarkers of adverse outcomes." Circulation 135.5 (2017) : 449-459.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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