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Glurate

Glurate (4-Acetylbutyric acid) is an acylating agent. Glurate can be used in the development of antiviral compounds, especially those targeting retroviruses such as herpes virus and HIV. Glurate can be used in the synthesis of acyclic nucleoside derivatives and 5-hydroxyhexanoic acid[1][2].

Product Specifications

Product Name Alternative

4-Acetylbutyric acid; 5-Oxohexanoic acid; NSC-5281

UNSPSC

12352211

Hazard Statement

H315, H319

Target

Drug Intermediate; HIV

Type

Reference compound

Related Pathways

Anti-infection; Others

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/glurate.html

Concentration

10mM

Purity

99.88

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(=O)CCCC(=O)O

Molecular Formula

C6H10O3

Molecular Weight

130.14

Precautions

H315, H319

References & Citations

[1]Per Engelhardt, et al. Synthesis of acyclic nucleosides. Patent WO1997030052A1.|[2]Valentin H E, et al. Identification of 5-hydroxyhexanoic acid, 4-hydroxyheptanoic acid and 4-hydroxyoctanoic acid as new constituents of bacterial polyhydroxyalkanoic acids. Applied microbiology and biotechnology, 1996, 46: 261-267.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W001957/Glurate-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W001957/Glurate-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

Phase 1

CAS Number

[3128-06-1]

Available Sizes

Curated Selection

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