FLT3-IN-2
FLT3-IN-2 (Compound P-0266) is a FLT3 inhibitor with an IC50 of [1][2].
Product Specifications
CAS Number
923562-23-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
FLT3
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/FLT3-IN-2.html
Concentration
10mM
Purity
98.80
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=C1)(F)F
Molecular Formula
C21H16ClF3N4
Molecular Weight
416.83
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang, Chao, et al. Kinase modulation for the treatment of leukemias. From PCT Int. Appl. (2012), WO 2012158957 A2 20121122.|[2]Zhang Chao, et al. 7-Azaindole derivatives and their preparation, pharmaceutical compositions and use for modulating c-kit and c-fms activity. From PCT Int. Appl. (2007), WO 2007013896 A2 20070201.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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