FLT3-IN-2

FLT3-IN-2 (Compound P-0266) is a FLT3 inhibitor with an IC50 of [1][2].

Product Specifications

CAS Number

[923562-23-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

FLT3

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/FLT3-IN-2.html

Concentration

10mM

Purity

98.80

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=C1)(F)F

Molecular Formula

C21H16ClF3N4

Molecular Weight

416.83

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhang, Chao, et al. Kinase modulation for the treatment of leukemias. From PCT Int. Appl. (2012), WO 2012158957 A2 20121122.|[2]Zhang Chao, et al. 7-Azaindole derivatives and their preparation, pharmaceutical compositions and use for modulating c-kit and c-fms activity. From PCT Int. Appl. (2007), WO 2007013896 A2 20070201.