Purified Anti-Human CD38 Antibody[AT13/5]
Product Specifications
Background
CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD (P) + into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose . CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells . Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
Abbreviation
CD38
Gene ID
952
UniProt
P28907
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD38 protein
Target
CADPr hydrolase; ADP-ribosyl cyclase; cyclic ADP-ribose hydrolase; Acute lymphoblastic leukemia cells antigen CD; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; CD38; ADPRC 1; ADPRC1; Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; ADP-ribosyl; T10; cyclase;2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1 (ADPRC 1) ; Cyclic ADP-ribose hydrolase 1 (cADPr hydrolase 1) ; cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase; ADP ribosyl cyclase; ADPRC1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; T10; Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase; ADPRC1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; T10; ADP ribosyl cyclase 1; ADP ribosyl cyclase/cyclic ADP-ribose hydrolase; CD 38; CD38 antigen (p45) ; Cd38-rs1; Cyclic ADP ribose hydrolase 1; Ecto nicotinamide adenine dinucleotide glycohydrolase; I19 (mouse) ; Lymphocyte differentiation antigen CD38; NAD (+) nucleosidase; NIM-R5 antigen; NIMR5 antigen (mouse) ; OTTHUMP00000158633; OTTHUMP00000217743
Clonality
Monoclonal
Clone
AT13/5
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Stem Cells; Cancer; Metabolism
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Mouse IgG1, κ
Available Sizes
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