Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Harringtonolide

Harringtonolide is a potent RACK1 inhibitor (IC50=39.66 μM in A375 cells) . Harringtonolide inhibits the epithelial-mesenchymal transition (EMT) process and cell proliferation by affecting the interaction between FAK and RACK1. Harringtonolide has plant growth inhibitory, antiviral, anti-inflammatory, and antiproliferation activities[1].

Product Specifications

CAS Number

64761-48-4

UNSPSC

12352005

Target

FAK

Type

Natural Products

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-anti-virus

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/harringtonolide.html

Purity

98.0

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C=C(CC2)C3=C([C@H]4C(C5O6)C3[C@@]2([C@H](C)[C@H]5O4)C6=O)C(C)=C1

Molecular Formula

C19H18O4

Molecular Weight

310.34

References & Citations

[1]Zhu TY, et al. Photoaffinity Probe Reveals the Potential Target of Harringtonolide for Cancer Cell Migration Inhibition. ACS Med Chem Lett. 2022;13 (3) :449-456. Published 2022 Feb 2.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ZIM2 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI7G1]
TA502066AM 100 µL

ZIM2 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI7G1]

Sign In for Pricing
View Details
HCCA2 (MOB2) (NM_001172223) Human Over-expression Lysate
LC432798 20 µg

HCCA2 (MOB2) (NM_001172223) Human Over-expression Lysate

Sign In for Pricing
View Details
Glycerol-d5
TRC-G598402-1G 1 g

Glycerol-d5

Sign In for Pricing
View Details
T-bet Rabbit Polyclonal Antibody
ER1802-65 100 µL

T-bet Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
5HT6 Receptor (HTR6) (C-term) Rabbit Polyclonal Antibody
AP10420PU-N 50 µg

5HT6 Receptor (HTR6) (C-term) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Human Syntaxin 18 (STX18) activation kit by CRISPRa
GA110015 1 Kit

Human Syntaxin 18 (STX18) activation kit by CRISPRa

Sign In for Pricing
View Details