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BTF Recombinant Rabbit Monoclonal Antibody [JE77-57]

Bcl-2-associated transcription factor 1 is a Bcl-2 family protein in humans that is encoded by the BCLAF1 gene. This gene encodes a transcriptional repressor that interacts with several members of the BCL-2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different protein isoforms have been found for this gene.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Bcl 2 associated transcription factor antibody Bcl-2-associated transcription factor 1 antibody BCL2 associated transcription factor 1 antibody BCLAF1 antibody BCLF1_HUMAN antibody bK211L9.1 antibody Btf antibody KIAA0164 antibody

Abbreviation

BCLAF1, BTF, KIAA0164

Swiss Prot

Q9NYF8 Human, Q8K019 Mouse,

Cellular Locus

Cytoplasm, Nucleus, Nucleus speckle, nucleoplasm.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within Human BTF aa 51-150 / 920.

Isotype

IgG

Clone

JE77-57

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

HEK-293 cell lysate, HeLa cell lysate, NIH/3T3 cell lysate, C6 cell lysate, rat testis tissue lysate, HEK-293, NIH/3T3, C6, human colon tissue, human testis tissue, mouse colon tissue, mouse testis tissue, rat colon tissue, rat testis tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:200-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 106 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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