Glucokinase

Glucokinase is a glucose-phosphorylating enzyme that has an important role in glucose homeostasis. Glucokinase acts as a glucose sensot of pancreatic β-cells. Glucokinase regulates the conversion of glucose to glucogen as well as gluconeogenesis. Glucokinase in mammals can phosphorylate hexoses like mannose or fructose in addition to glucose. Glucokinase can be studied in research on diabetes[1][2].

Product Specifications

CAS Number

[9001-36-9]

UNSPSC

12352204

Target

Biochemical Assay Reagents

Type

Enzyme

Related Pathways

Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glucokinase.html

Solubility

H2O : ≥ 50 mg/mL

Smiles

[Glucokinase]

References & Citations

[1]Matschinsky F. M. (2009) . Assessing the potential of glucokinase activators in diabetes therapy. Nature reviews. Drug discovery, 8 (5), 399-416. |[2]Iynedjian P. B. (2009) . Molecular physiology of mammalian glucokinase. Cellular and molecular life sciences : CMLS, 66 (1), 27-42.