6-Chloro-9- (2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl) -9H-purine
Selected Variant
HY-W544503
Size: 1 Each
6-Chloro-9- (2,3,5-tri-O-benzoyl-2-C-methyl-beta-D-ribofuranosyl) -9H-purine dibenzoate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
205171-04-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-chloro-9-2-3-5-tri-o-benzoyl-2-c-methyl-beta-d-ribofuranosyl-9h-purine.html
Solubility
10 mM in DMSO
Smiles
C[C@@]1(OC(C2=CC=CC=C2)=O)[C@H](OC(C3=CC=CC=C3)=O)[C@@H](COC(C4=CC=CC=C4)=O)O[C@H]1N5C=NC6=C5N=CN=C6Cl
Molecular Formula
C32H25ClN4O7
Molecular Weight
613.02
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Price
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