Nicotelline
Nicotelline (Nicotellin) is a nicotine-related alkaloid, as well as a weak inhibitor of human cDNA-expressed cytochrome P-450 2A6 (CYP2A6) . CYP2A6 mediates coumarin 7-hydroxylation, while Nicotelline fails to exhibit inhibition at 300 μM. Nicotelline can be used as a tracer and biomarker of particulate matter (PM) derived from tobacco smoke[1][2].
Product Specifications
CAS Number
494-04-2
Product Name Alternative
Nicotellin
UNSPSC
12352005
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nicotelline.html
Concentration
10mM
Purity
98.88
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C1(C2=CC=NC(C3=CN=CC=C3)=C2)=CN=CC=C1
Molecular Formula
C15H11N3
Molecular Weight
233.27
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP26
Available Sizes
Frequently Asked Questions
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