LM22A-4
LM22A-4 is a specific agonist of tyrosine kinase receptor B, used for neurological disease research.
Product Specifications
CAS Number
37988-18-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Trk Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/LM22A-4.html
Concentration
10mM
Purity
98.81
Solubility
DMSO : ≥ 29 mg/mL|H2O : ≥ 50 mg/mL
Smiles
O=C(C1=CC(C(NCCO)=O)=CC(C(NCCO)=O)=C1)NCCO
Molecular Formula
C15H21N3O6
Molecular Weight
339.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Yu G, et al. Protective effects of LM22A-4 on injured spinal cord nerves. Int J Clin Exp Pathol. 2015 Jun 1;8 (6) :6526-32. eCollection 2015.|[2]Kajiya M, et al. BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB-ERK/Akt signaling cascade. Int Immunopharmacol. 2014 Apr;19 (2) :245-52
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TP312577M 100 µg
Espin (ESPN) (NM_031475) Human Recombinant Protein
Sign In for Pricing
View Details 
BNC680890-500 1x 500 µL
NGFR (Nerve Growth Factor Receptor) (NGFR5), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
