LM22A-4
LM22A-4 is a specific agonist of tyrosine kinase receptor B, used for neurological disease research.
Product Specifications
CAS Number
[37988-18-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Trk Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/LM22A-4.html
Concentration
10mM
Purity
98.81
Solubility
DMSO : ≥ 29 mg/mL|H2O : ≥ 50 mg/mL
Smiles
O=C(C1=CC(C(NCCO)=O)=CC(C(NCCO)=O)=C1)NCCO
Molecular Formula
C15H21N3O6
Molecular Weight
339.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Yu G, et al. Protective effects of LM22A-4 on injured spinal cord nerves. Int J Clin Exp Pathol. 2015 Jun 1;8 (6) :6526-32. eCollection 2015.|[2]Kajiya M, et al. BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB-ERK/Akt signaling cascade. Int Immunopharmacol. 2014 Apr;19 (2) :245-52
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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