CD43 rabbit pAb

The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. [provided by RefSeq, Sep 2011],

Product Specifications

Background

UniProt

P16150

Swiss Prot

P16150

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human CD43 AA range: 1-80

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:1000-2000 ELISA 1:5000-20000

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Membrane ; Single-pass type I membrane protein . Cell projection, microvillus . Cell projection, uropodium . Localizes to the uropodium and microvilli via its interaction with ERM proteins (EZR, RDX and MSN) . .; [CD43 cytoplasmic tail]: Nucleus . Nucleus, PML body . The sumoylated form localizes to the PML body. .