PIN1 inhibitor 3
PIN1 inhibitor 3 (Compound A0) is a PIN1 inhibitor, with a KD of 25 nM and an IC50 of 150 nM. PIN1 inhibitor 3 can be used as a target protein ligand for the synthesis of PROTAC. PIN1 inhibitor 3 can be utilized in cancer research[1].
Product Specifications
CAS Number
[3039570-04-9]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; PIN1
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pin1-inhibitor-3.html
Smiles
CC1=CC=CC=C1C2(CC2)C(NC(C(NC(CC3)CCN3C)=O)CC(N=N4)=CN4C(C=C5)=CC=C5C(C=C6)=CC=C6C#N)=O
Molecular Formula
C35H37N7O2
Molecular Weight
587.71
References & Citations
[1]Liu C, et al. Re-Evaluating PIN1 as a Therapeutic Target in Oncology Using Neutral Inhibitors and PROTACs. J Med Chem. 2024 Sep 12;67 (17) :15780-15795.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
042349-Biotin 200 µL
ST3GAL5, CT (ST3GAL5, SIAT9, Lactosylceramide alpha-2,3-sialyltransferase, CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase, Ganglioside GM3 synthase, ST3Gal V, Sialyltransferase 9) (Biotin) discontinued
Sign In for Pricing
View Details 
K2626703 1.0 µg DNA
WBP11 sgRNA CRISPR Lentivector (Human) (Target 2)
Sign In for Pricing
View Details 
144964-PE 100 µL
NFKB1 (KBF1, NF-kappaB, NFkappaB, NF-kB1, NFKB-p50, EBP-1, p50, p105, TRANSCRIPTION FACTOR NFKB1, DNA-binding factor KBF1, NFKB p50, INCLUDED, NFKB p105, INCLUDED, Nuclear factor of kappa light polypeptide gene enhancer in B Cells 1) (PE) discontinued
Sign In for Pricing
View Details 