AHR-13268D

AHR-13268D is an oral active antiallergic and antihistaminic agent, with bioavailable approximately 88%. AHR-13268D is a potent inhibitor of histamine release from rat peritoneal mast cells, with the IC50 of 0.51 nM[1].

Product Specifications

CAS Number

[130838-11-8]

UNSPSC

12352005

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ahr-13268d.html

Smiles

O=C(C1=CC=C(C=C1)OCCCN2CCC(CC2)C(C3=CC=C(C=C3)F)(O)C4=CC=C(C=C4)F)O[Na]

Molecular Formula

C28H28F2NNaO4

Molecular Weight

503.51

References & Citations

[1]J C Nolan, et al. The in vivo and in vitro activity of AHR-13268D, a new antiallergic/antihistaminic agent. Agents Actions. 1990 Nov;31 (3-4) :210-8.