3'-Hydroxypuerarin

3'-Hydroxypuerarin is an isoflavone isolated from the roots of Pueraria lobata (Willd.) Ohwi. 3'-Hydroxypuerarin is a antioxidant, which shows marked ONOO (-), NO•, total ROS scavenging activities[1][2][3].

Product Specifications

CAS Number

[117060-54-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/3-hydroxypuerarin.html

Purity

99.44

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C(C2=CC=C(O)C(O)=C2)=COC3=C([C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)C(O)=CC=C13

Molecular Formula

C21H20O10

Molecular Weight

432.38

Precautions

H302, H315, H319

References & Citations

[1]Sun Y, et al. New hepatoprotective isoflavone glucosides from Pueraria lobata (Willd.) Ohwi. Nat Prod Res. 2018 Jul 3:1-8.|[2]Zhang CL, et al. Comparative study of Puerariae lobatae and Puerariae thomsonii by HPLC-diode array detection-flow injection-chemiluminescence coupled with HPLC-electrospray ionization-MS. Chem Pharm Bull (Tokyo) . 2011;59 (5) :541-5.|[3]Jin SE, et al. Anti-inflammatory and antioxidant activities of constituents isolated from Pueraria lobata roots. Arch Pharm Res. 2012 May;35 (5) :823-37.