Purified Anti-Human CD163 Antibody[MAC2-158]
Product Specifications
Background
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Abbreviation
CD163
Gene ID
9332
UniProt
Q86VB7
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD163 protein
Target
GHI/; SCARI; CD163; M130; MM130; SCARI1; ED2 (rat) ; GHI/61; Hemoglobin/Haptoglobin Complex Receptor; macrophage-associated antigen; p155; RM3/1; GHI/61
Clonality
Monoclonal
Clone
MAC2-158
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Cardiovascular
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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