Gemcitabine triphosphate (trisodium)
Gemcitabine triphosphate (trisodium) is one of the two nucleoside metabolites of Gemcitabine (HY-17026) in cells. The other is active diphosphate (dFdDTP) . Gemcitabine triphosphate can be used as a standard in radio-labeled probe imaging studies, to identify tumors sensitive to Gemcitabine, and to evaluate Gemcitabine uptake and retention by cells[1].
Product Specifications
Product Name Alternative
DFdCTP (trisodium)
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gemcitabine-triphosphate-trisodium.html
Concentration
100 mM * 175.72 μL in Water
Purity
99.65
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
NC(C=CN1[C@H]2C(F)(F)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)=NC1=O
Molecular Formula
C9H11F2N3Na3O13P3
Molecular Weight
569.08
References & Citations
[1]Shewach DS, et al. Gemcitabine and radiosensitization in human tumor cells. Invest New Drugs. 1996;14 (3) :257-63.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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