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(rel)-PROTAC ERRα Degrader-1

Product Specifications

UNSPSC Description

(rel)-PROTAC ERRα Degrader-1 is a relative configuration of PROTAC ERRα Degrader-1. PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an estrogen-related receptor alpha (ERRa) degrader[1].

Target Antigen

Estrogen Receptor/ERR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/rel-protac-err-alpha-degrader-1.html

Purity

98.18

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N(CCN1CC(NCCNC(/C(C#N)=C/C2=CC(OC)=C(OCC(C=CC(C(F)(F)F)=C3)=C3C(F)(F)F)C=C2)=O)=O)CC1=O)N4[C@@H](C5=CC=C(Cl)C=C5)[C@@H](C6=CC=C(Cl)C=C6)N=C4C(C=CC(OC)=C7)=C7OC(C)C

Molecular Weight

1108.92

References & Citations

[1]Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-128838A/rel-PROTAC-ERRα-Degrader-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-128838A/rel-PROTAC-ERRα-Degrader-1-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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