(rel) -PROTAC ERRα Degrader-1
(rel) -PROTAC ERRα Degrader-1 is a relative configuration of PROTAC ERRα Degrader-1. PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an estrogen-related receptor alpha (ERRa) degrader[1].
Product Specifications
UNSPSC
12352005
Target
Estrogen Receptor/ERR; PROTACs
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rel-protac-err-alpha-degrader-1.html
Purity
98.18
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(CCN1CC(NCCNC(/C(C#N)=C/C2=CC(OC)=C(OCC(C=CC(C(F)(F)F)=C3)=C3C(F)(F)F)C=C2)=O)=O)CC1=O)N4[C@@H](C5=CC=C(Cl)C=C5)[C@@H](C6=CC=C(Cl)C=C6)N=C4C(C=CC(OC)=C7)=C7OC(C)C
Molecular Formula
C54H49Cl2F6N7O8
Molecular Weight
1108.92
References & Citations
[1]Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10 (5) :767-772.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15369783 1 Vial
Lentiviral human GPD1 sgRNA gene knockout kit - Lentiviral human GPD1 sgRNA gene knockout kit (25)
Ask
View Details 
244990-ML490 100 µL
CSF2 (Colony Stimulating Factor 2 (Granulocyte-Macrophage), GMCSF, MGC131935, MGC138897) (MaxLight 490)
Ask
View Details 
M2360-02S-APC 100 µL
MAP Kinase 3 (Mitogen-activated Protein Kinase 3, MAPK 3, Mapk3, ERT2, Extracellular Signal-regulated Kinase 1, ERK1, ERK-1, Esrk1, Insulin-stimulated MAP2 Kinase, MAP Kinase Isoform p44, Microtubule-associated Protein 2 Kinase, Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, MAPK1, MNK1, p44, p44erk1, p44-ERK1, p44mapk, p44-MAPK, Prkm3) (APC) discontinued
Ask
View Details