(±) 4-HDHA

(±) 4-HDHA (4-Hydroxy docosahexaenoic acid) is an autoxidation product of Docosahexaenoic acid (HY-B2167) (DHA) . (±) 4-HDHA is a PPARγ agonist, antidiabetic and anti-inflammatory agent[1][2].

Product Specifications

CAS Number

[90906-40-4]

Product Name Alternative

4-Hydroxy docosahexaenoic acid; (±) 4-HDoHE

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/racemic-4-hdha.html

Concentration

2.90 mM * 25 μL in Methanol

Purity

99.05

Smiles

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C=C\C(O)CCC(O)=O

Molecular Formula

C22H32O3

Molecular Weight

344.49

Precautions

H302, H315, H319, H335

References & Citations

[1]Yamamoto K, et al. 4-Hydroxydocosahexaenoic acid, a potent peroxisome proliferator-activated receptor gamma agonist alleviates the symptoms of DSS-induced colitis. Biochem Biophys Res Commun. 2008 Mar 14;367 (3) :566-72. |[2]Richard Louis Dunbar, et al. Lymph-releasing compositions of fatty acids and uses thereof for lymphatic incorporation and systemic disease treatment. Patent. WO2023146984.