Carvacrol
Product Specifications
UNSPSC Description
Carvacrol is an orally active monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations[1][2].
Target Antigen
Apoptosis; Bacterial; Endogenous Metabolite; Fungal; Notch
Type
Natural Products
Related Pathways
Anti-infection;Apoptosis;Metabolic Enzyme/Protease;Neuronal Signaling;Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/carvacrol.html
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC(C(C)C)=CC=C1C
Molecular Weight
150.221
References & Citations
[1]Khan F, et al. Carvacrol Induced Program Cell Death and Cell Cycle Arrest in Androgen-Independent Human Prostate Cancer Cells via Inhibition of Notch Signaling. Anticancer Agents Med Chem. 2019 Jul 31.|[2]Suntres ZE, et al. The bioactivity and toxicological actions of carvacrol. Crit Rev Food Sci Nutr. 2015;55(3):304-18.|[3]Kara M, et al. Supplemental carvacrol can reduce the severity of inflammation by influencing the production of mediators of inflammation. Inflammation. 2015;38(3):1020-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0711/Carvacrol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0711/Carvacrol-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
499-75-2
Available Sizes
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