Parstatin (mouse) (TFA)

Parstatin (mouse) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis[1][2].

Product Specifications

UNSPSC

12352209

Target

Protease Activated Receptor (PAR)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/parstatin-mouse-tfa.html

Purity

99.71

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

OC(C(F)(F)F)=O.O=C([C@@H](N)CCSC)NCC(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N5[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CCC5)=O)CC(N)=O)=O)C(C)C)=O)[C@@H](C)O)=O)C)=O)CC(O)=O)=O)[C@@H](C)O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CO)=O)CCC(O)=O)=O)CCC4)=O)CCC(N)=O)=O)CO)=O)CCSC)=O)CCC3)=O)C(C)C)=O)CCCNC(N)=N)=O)CO)=O)CO)=O)CC(C)C)=O)CC(C)C)=O)CCC2)=O)=O)CS)=O)CC(C)C)=O)CO)=O)CC(C)C)=O)=O)CC(C)C)=O)C)=O)C(C)C)=O)[C@H](CC)C)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC1)=O

Molecular Formula

C191H327F3N58O59S3

Molecular Weight

4533.18

References & Citations

[1]Panagiota Zania, et al. Parstatin, the Cleaved Peptide on Proteinase-Activated Receptor 1 Activation, Is a Potent Inhibitor of Angiogenesis. J Pharmacol Exp Ther. 2009 Feb;328 (2) :378-89.|[2]Jennifer L Strande, et al. Parstatin: A Cryptic Peptide Involved in Cardioprotection After Ischaemia and Reperfusion Injury. Cardiovasc Res. 2009 Jul 15;83 (2) :325-34.