NPFF1-R antagonist 1
NPFF1-R antagonist 1 (compound 8b), a piperidine analogue, is a potent neuropeptide FF (NPFF) receptor antagonist. NPFF1-R antagonist 1 is 15-fold selective for the NPFF1-R subtype, with Ki values of 211 nM and 3270 nM for NPFF1-R and NPFF2-R, respectively[1].
Product Specifications
CAS Number
[3057753-40-6]
UNSPSC
12352005
Target
Neuropeptide FF Receptor; Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/npff1-r-antagonist-1.html
Solubility
10 mM in DMSO
Smiles
O=C(CN1CCC(CC2=CC=CC=C2)CC1)NCC3(CCN(CC4=CC=CC=C4)CC3)NC5=C(C=CC=C6)C6=CC=C5
Molecular Formula
C37H44N4O
Molecular Weight
560.77
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NPFFR1; NPFFR2; δ Opioid Receptor/DOR; κ Opioid Receptor/KOR; μ Opioid Receptor/MOR
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items